Rapid and cost-effective multiresidue analysis of pharmaceuticals, personal care products, and antifouling booster biocides in marine sediments using matrix solid phase dispersion

Currently, there are many contaminants of concern that need to be accurately determined help assess their potential environmental hazard. Despite increasing interest, yet few occurrence data exist, likely because they present at low levels and in very complex matrices. Therefore, multiresidue analytical methods for determination highly sensitive, selective, robust. Particularly, due the trace these chemicals environment, an extensive extraction procedure is required before determination. This work details development a fast cheap vortex-assisted matrix solid-phase dispersion-high performance liquid chromatography tandem-mass spectrometry (VA-MSPD-HPLC-MS/MS) method 59 emerging (CECs) including pharmaceuticals, personal care products, booster biocides, sediment. The validated provided high sensitivity (0.42–36.8 ngg−1 dw quantification limits), wide good linearity (r2 > 0.999), satisfactory accuracy (60–140%), precision below 20% most target analytes. In comparison with previous methods, relying on traditional techniques, proposed demonstrated more environmentally friendly, cheaper, simpler, faster. was applied monitor compounds sediments collected Brazil, using only 2 g sediment samples, free-solid support, 5 mL methanol as solvent. UV filter avobenzone, stabilizer antifreeze methylbenzotriazole, preservative methylparaben, fluoroquinolone antibiotic ciprofloxacin, biocides irgarol 4,5-dichloro-2-octyl-4-isothiazolin-3-one were concentrations range 1.44–69.7 dw.